Koox Maraykan ah ayaa soo jeedisay hab cusub oo lagu hagaajinayo laysarka microdisk

Koox cilmi-baaris oo wadajir ah oo ka socda Dugsiga Caafimaadka Harvard (HMS) iyo Isbitaalka Guud ee MIT ayaa sheegay inay ku guuleysteen hagaajinta wax soo saarka laser microdisk iyadoo la adeegsanayo habka PEC etching, taasoo ka dhigaysa ilo cusub oo nanophotonics ah iyo biomedicine " rajo leh."

(Wax soo saarka laser-ka microdisk waxaa lagu hagaajin karaa habka etching PEC)

In beeraha eenanophotonicsiyo biomedicine, microdiskleysarkaiyo laysarka nanodisk waxay noqdeen kuwo rajo lehilaha iftiinkaiyo baaritaanno. Codsiyo badan oo ay ka mid yihiin isgaarsiinta sawirka-chip-ka, bioimaging on-chip bioimaging, biochemical dareenka, iyo habaynta macluumaadka photon quantum, waxay u baahan yihiin si ay u gaaraan wax soo saarka laysarka si loo go'aamiyo dhererka iyo saxnaanta band ultra-cidhiidhi ah. Si kastaba ha ahaatee, way adag tahay in la soo saaro microdisk iyo nanodisk lasers ee mawjaddan saxda ah ee cabbir ballaaran. Nidaamyada nanofabrication ee hadda jira waxay soo bandhigaan randomness ee dhexroor disc, taas oo ka dhigaysa in ay adag tahay in la helo mawjada go'an ee farsamaynta mass laser iyo wax soo saarka. Hadda, koox ka mid ah cilmi-baarayaasha Harvard Medical School iyo Massachusetts General Hospital ee Wellman Center for.Daawooyinka indhaha Elektarooniga ahwaxay soo saartay farsamo cusub oo optochemical ah (PEC) oo gacan ka geysanaysa in si sax ah loo habeeyo hirarka laser-ka ee leysarka microdisk saxnaanta subnanometer-ka. Shaqada waxaa lagu daabacay joornaalka Advanced Photonics.

Sawir kiimiko cuncun
Sida laga soo xigtay warbixinnada, habka cusub ee kooxda ayaa awood u siinaya soo saarista laysarka yar-yar ee diskka iyo nanodisk laser arrays leh saxan, dhererka qiiqa sii daaya. Furaha horumarkan waa isticmaalka PEC etching, kaas oo siinaya hab wax ku ool ah oo la miisaami karo si loo hagaajiyo hirarka dhererka leysarka microdisc. Natiijooyinka kor ku xusan, kooxdu waxay si guul leh u heleen indium Gallium arsenide fossfating microdisks oo lagu daboolay silica qaab dhismeedka tiirka fosfide indium. Kadibna waxay hagaajiyeen hirarka dhererka leysarka ee microdisks-yadan si sax ah qiime go'an iyaga oo fulinaya etching photochemical ee xal la qasi karo oo ah sulfuric acid.
Waxay kaloo baareen hababka iyo dhaq-dhaqaaqyada sawir-kiimeedka gaarka ah (PEC) etchings. Ugu dambayntii, waxay ku wareejiyeen mawjadaha-mawjadaha-mawjadaha-ku-habboon ee isku-xidhka microdisk-ka dul-saar polydimethylsiloxane si ay u soo saaraan qaybo laser go'doonsan oo madax-banaan Microdisk-ka soo baxay wuxuu muujinayaa xajmi-ballaaran ultra-ballaaran ee qiiqa laysarka, oo lehleysarkadhinaca tiirka in ka yar 0.6 nm iyo qayb go'doonsan oo ka yar 1.5 nm.

Furitaanka albaabka codsiyada biomedical
Natiijadani waxay albaabka u furaysaa nanophotonics badan oo cusub iyo codsiyo caafimaad. Tusaale ahaan, leysarka microdisk-ka keligood ah waxay u adeegi karaan sida barcode physico-optical barcodes oo loogu talagalay shaybaarada noolaha ee kala duwan, taas oo awood u siinaysa calaamadaynta noocyada unugyada gaarka ah iyo bartilmaameedka molecules gaarka ah ee falanqaynta multiplex. Calaamadaynta nooca-gaar ah ee unugyada hadda waxaa lagu sameeyaa iyadoo la adeegsanayo biomarkers caadiga ah, sida sida fluorophores organic, dhibco quantum ah, iyo kuul fluorescent, kuwaas oo leh ballac dhexdeed oo sii daaya. Haddaba, dhawr nooc oo unug oo gaar ah ayaa isku mar lagu calaamadayn karaa. Taas bedelkeeda, qiiqa aadka u cidhiidhiga ah ee laysarka microdisk wuxuu awood u yeelan doonaa inuu aqoonsado noocyo badan oo unug ah isku mar.
Kooxdu waxay tijaabisay oo si guul leh u soo bandhigtay qaybo leyssar microdisk ah oo si sax ah loo habeeyay sida biomarkers, iyaga oo isticmaalaya si ay ugu calaamadiyaan unugyada epithelial naaska caadiga ah MCF10A. Siideynta ultra-ballaaran ee aadka u ballaaran, laysarkani waxa ay suurtogal u noqon karaan in ay wax ka beddelaan biosensing, iyaga oo isticmaalaya farsamooyinka biomedical iyo indhaha la xaqiijiyay sida sawirka cytodynamic, cytometry socodka, iyo falanqaynta multi-omics. Tiknoolajiyada ku saleysan etching PEC waxay calaamad u tahay horumarka weyn ee leysarka microdisk. Miisaanka habka, iyo sidoo kale saxnaanta subnanometer-ka, ayaa furaysa fursado cusub oo loogu talagalay codsiyada aan la tirin karin ee leysarka ee nanophotonics iyo qalabka noolaha, iyo sidoo kale barcodes loogu talagalay dadka unugyada gaarka ah iyo molecules falanqaynta.