Koox Mareykan ah ayaa soo jeedisay hab cusub oo lagu hagaajinayo laysarka microdisk

Koox cilmi-baaris oo wadajir ah oo ka socota Harvard Medical School (HMS) iyo MIT General Hospital ayaa sheegay inay ku guuleysteen hagaajinta wax soo saarka laysarka microdisk iyagoo adeegsanaya habka PEC etching, taasoo ka dhigaysa ilo cusub oo loogu talagalay nanophotonics iyo biomedicine "mid rajo leh."

(Wax soo saarka laser-ka microdisk waxaa lagu hagaajin karaa habka PEC etching)

Beerahananofotonicsiyo bayomedicine, microdisklaysarkaiyo laysarka nanodisk ayaa noqday kuwo rajo lehilo iftiiniyo baaritaanno. Adeegsiyo dhowr ah sida isgaarsiinta photonic-ka ee chip-ka, sawir-qaadista bio-chip-ka, dareemaha biochemical, iyo habaynta macluumaadka photon-ka ee quantum, waxay u baahan yihiin inay gaaraan wax soo saarka laysarka si loo go'aamiyo hirarka iyo saxnaanta xarigga aadka u cidhiidhiga ah. Si kastaba ha ahaatee, way adag tahay in la soo saaro laysarka microdisk iyo nanodisk ee hirarkan saxda ah ee baaxadda weyn. Hawsha nano-fabrication ee hadda jirta waxay soo bandhigaysaa kala soocidda dhexroorka saxanka, taas oo adkeyneysa in la helo hirar go'an oo ku jira habaynta iyo soo saarista cufnaanta laysarka. Hadda, koox cilmi-baarayaal ah oo ka socda Dugsiga Caafimaadka Harvard iyo Xarunta Wellman ee Isbitaalka Guud ee Massachusetts ayaa uDaawada Optoelectronic-kawaxay soo saartay farsamo cusub oo lagu sawirayo indhaha (optochemical) (PEC) oo gacan ka geysaneysa in si sax ah loo hagaajiyo hirarka laysarka ee laysarka microdisk iyadoo la adeegsanayo saxnaanta subnanometer. Shaqada waxaa lagu daabacay joornaalka Advanced Photonics.

Qalin sawireed
Sida laga soo xigtay warbixinnada, habka cusub ee kooxdu wuxuu suurtogal ka dhigayaa soo saarista laysarka yar yar iyo nanodisk laser arrays oo leh hirarka qiiqa ee saxda ah oo hore loo sii go'aamiyay. Furaha guushan waa isticmaalka PEC etching, kaas oo bixiya hab wax ku ool ah oo la miisaami karo si loo hagaajiyo hirarka laysarka yar yar. Natiijooyinka kor ku xusan, kooxdu waxay si guul leh u heshay indium Gallium arsenide phosphating microdisks oo lagu daboolay silica qaab-dhismeedka tiirka indium phosphide. Kadib waxay si sax ah u hagaajiyeen hirarka laysarka ee microdisks-yadan iyagoo samaynaya sawir-qaadis photochemical ah oo ku jira xal la qasi jiray oo ah sulfuric acid.
Waxay sidoo kale baareen hababka iyo dhaqdhaqaaqa sawirrada gaarka ah ee sawir-qaadista kiimikada (PEC). Ugu dambeyntii, waxay u wareejiyeen safka microdisk-ka ee mowjadaha lagu hagaajiyay substrate polydimethylsiloxane ah si ay u soo saaraan walxo laysar oo madax-bannaan oo go'doonsan oo leh hirarka laysarka ee kala duwan. Microdisk-ka ka dhashay wuxuu muujinayaa ballaca aadka u ballaaran ee sii deynta laysarka, iyadoo la adeegsanayolaysartiirka ka yar 0.6 nm iyo walxaha go'doonsan ee ka yar 1.5 nm.

Furitaanka albaabka codsiyada bayoolajiga
Natiijadani waxay albaabka u furaysaa barnaamijyo badan oo cusub oo nanofotonics ah iyo barnaamijyo biomedical ah. Tusaale ahaan, laysarka microdisk-ka ee keligood taagan waxay u adeegi karaan sida barkodyada fiisiko-optic ee muunadaha bayoolojiga ee kala duwan, taasoo suurtogalinaysa calaamadaynta noocyada unugyada gaarka ah iyo bartilmaameedka molecules-ka gaarka ah ee falanqaynta multiplex. Calaamadaynta nooca unugyada gaarka ah hadda waxaa lagu sameeyaa iyadoo la adeegsanayo biomarkers-ka caadiga ah, sida fluorophores-ka dabiiciga ah, dhibcaha quantum, iyo kuul fluorescent, kuwaas oo leh ballaca qulqulka hawada oo ballaaran. Sidaa darteed, dhowr nooc oo unugyo gaar ah ayaa lagu calaamadayn karaa isku mar. Taas bedelkeeda, sii deynta iftiinka aadka u cidhiidhiga ah ee laysarka microdisk waxay awood u yeelan doontaa inay aqoonsato noocyo badan oo unugyo ah isla waqtigaas.
Kooxdu waxay tijaabisay oo si guul leh u muujisay walxaha laysarka microdisk ee si sax ah loo hagaajiyay sida biomarkers, iyagoo adeegsanaya si ay ugu calaamadeeyaan unugyada epithelial-ka naasaha ee caadiga ah ee la beeray MCF10A. Iyada oo la adeegsanayo sii deynta band-ka aadka u ballaaran, laysarkani waxay kacaan ku samayn karaan biosensing, iyagoo adeegsanaya farsamooyin biomedical iyo optical ah oo la xaqiijiyay sida sawirka cytodynamic, cytometry socodka, iyo falanqaynta multi-omics. Tiknoolajiyadda ku salaysan PEC etching waxay calaamad u tahay horumar weyn oo ku yimid laysarka microdisk. Cabbiraadda habka, iyo sidoo kale saxnaanta subnanometer-ka, waxay furaysaa fursado cusub oo loogu talagalay codsiyada aan la tirin karin ee laysarka ee nanophotonics iyo aaladaha biomedical, iyo sidoo kale barcodes-ka loogu talagalay dadka gaarka ah ee unugyada iyo molecules-ka falanqaynta.